This Is The Mesothelioma And Asbestos Case Study You'll Never Forget
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Asbestos is a natural mineral that is found in long, thin fibres. Workers who are regularly exposed to asbestos risk developing lung diseases, such as mesothelioma.
It may take decades before symptoms begin to manifest after exposure to asbestos. Different types of asbestos can cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma is a cancer of the outer lung lining, or pleura. It is the most prevalent mesothelioma form and accounts for 70% to 79% of all diagnosed cases. This condition causes chest discomfort, shortness of breath, and a feeling of heaviness.
This kind of cancer is often caused by exposure to asbestos, which is a grouping of minerals that are composed of microscopic fibers. When inhaled, these fibers, cause irritation and DNA mutations. The pleura surrounds the lungs and chest cavity, so these irritations can affect both the lungs and a person's heart. Mesothelioma usually doesn't show symptoms until 30 to 50 year after exposure.
Chest pain and shortness breath are the most frequently reported symptoms. Patients may also suffer from chest tightness or coughing. They may also experience difficulty breathing. Patients with this cancer have a history that includes asbestos exposure at work. The most common jobs that expose workers to the risk of pleural mesothelioma include manufacturing, construction, and shipbuilding. People who have worked in the military could be at risk due to the frequent use of asbestos in Navy ships and bunkers for the army.
The TNM (tumors, lymph nodes, and metastases staging system) is the most popular staging system used to treat the pleural adenocarcinoma. The stage a patient has at diagnosis will aid their doctor in determining the best treatment plan for them. Patients with pleural mesothelioma that is in stage three or four will suffer a more negative prognosis compared to those who are in a less advanced stage. Stage four mesothelioma may be spread to the liver, heart or diaphragm. This can make it more difficult to treat and increases the risk of complications for patients.
Peritoneal Mesothelioma
As opposed to pleural mesothelioma that develops in the lung lining, peritoneal mesothelioma is found in the peritoneum -- an elongated membrane that covers the abdominal cavity and organs such as the intestines and the liver. Similar to pleural mesothelioma, asbestos exposure is the primary reason for peritoneal msothelioma. There are only 300-500 cases diagnosed each year this is less than pleural asbestosis.
Like pleural mesothelioma, the symptoms can take years to show. Patients typically suffer from abdominal pain and could also experience a mass in their abdomen. Symptoms of this type of mesothelioma may also include nausea as well as weight loss and fever. Many of these symptoms are similar to symptoms of digestive issues, which could cause confusion in diagnosis.
Generally, doctors can find mesothelioma by conducting a thorough health history and physical examination. Imaging tests like X-rays and CT scans are a way to identify mesothelioma. These tests can show tumors, as well as other signs of cancer that aren't visible on an X-ray.
These test results allow doctors to diagnose mesothelioma and determine the stage and suggest treatment options. The stage is determined by the kind of cell and if the cancer has spread.
The most significant mesothelioma risk factor is exposure to asbestos. People who have been in occupations that require asbestos case, like plumbing electrical work, manufacturing or construction, are at a higher risk of developing the disease. Even if someone isn't employed in one of these areas, he or she can be exposed to asbestos to asbestos through family members and other sources. Anyone who believes they may be at risk should speak with an expert. A mesothelioma specialist can help those who have a previous history of asbestos to find out more about their risk.
Risk Factors
Asbestos exposure is the primary mesothelioma risk factor, making up as much as 80 percent of cases. Exposure to asbestos can happen through military service, work, or living with people who have worked with asbestos. Asbestos particles are inhaled by people who are exposed to asbestos compensation. These irritate the linings and trigger cancerous cells to grow in the mesothelium. Mesothelioma can take between 15 and 60 years to develop after exposure to asbestos claim.
Other risk factors include smoking, genetics, and age. People in their 40s and 50s are more likely develop mesothelioma than those who are younger or older. This is because mesothelioma typically occurs between 20 and 60 years after the initial time of exposure before the first signs of cancer appear. It is important to note, too, that mesothelioma may be present in those who have been exposed to asbestos, but without having directly worked with it. This is known as indirect or secondary asbestos exposure. It can be as dangerous as direct asbestos exposure.
Smoking increases the risk of mesothelioma, because it damages the mesothelium. It also makes it more prone to. In addition, mesothelioma may be exacerbated by certain illnesses like asbestosis and pneumonia. Men are more likely to develop mesothelioma compared to women. This is because men are more likely to work with asbestos law and have an extended period of exposure than women. Men are also more likely to have lived with someone who has been exposed to asbestos, and to have asbestos fibers on their clothing. Women tend to have less exposure to asbestos and rarely carry asbestos lawsuit home on their clothing.
Diagnosis
Mesothelioma is a difficult cancer to diagnose because the symptoms are often similar to other conditions. This could lead to patients being incorrectly diagnosed.
NYU Langone doctors will perform physical examinations and document the patient's medical background including asbestos exposure. Doctors can also order a chest X-ray or CT scan to detect lumps or other abnormalities, and also to look for evidence of past asbestos exposure like plaques in the pleura (thickened pleura with calcium deposits) and the formation of fluid between the lung and the chest wall (known as the pleural effusion).
Other diagnostic tests include a magnetic resonance image, or MRI test, which makes use of magnets and radio waves to create a series of detailed images of the insides of the body. Another way for doctors to detect mesothelioma is through an operation called a biopsy. During a surgical biopsy, doctors take a small amount of tissue from the pleura or peritoneum for further analysis. A pathologist is then able to examine the tissue with microscopes to determine if it is contaminated with cancerous cells.
Mesothelioma can be classified based on the type of mesothelial cells involved, whether the cells are malignant or benign and the location, type, and stage of the tumor. Some types of mesothelioma have greater risk of metastasizing or spreading and it's crucial to determine the type of mesothelioma so that doctors can treat it prior to it becoming out-of-control.
Doctors may also conduct tests in the laboratory on tumors to identify specific proteins, genes or other elements that can help them describe cancer characteristics and determine the best treatment. These results are known as staging.
Treatment
A mesothelioma diagnosis is terrifying. However, it is important to keep in mind that the cancer is treatable, particularly in its earlier stages. Many patients with mesothelioma be afflicted for a long time, without spreading.
Exposure to asbestos may cause mesothelioma through a variety of ways. Asbestos fibres, too small to be felt or observed through the naked eye are able to become airborne and irritate the lining of the lung (pleura). As time passes irritation can lead to formation of scar tissue, which can cause changes in the cell structure that can eventually grow into tumors.
The Pleura is a protective layer that surrounds the lungs, heart and abdomen. Mesothelium consists of cells that react when exposed to asbestos. They cause inflammation of the tissue and cause it to become scarred. Overtime, these changes cause the development of malignant mesothelioma cancers.
The signs of pleural mesothelioma can include shortness of breath and chest pain as well as a buildup of fluid in the lung (pleural effusion). In rare cases cancer can spread to the tissues around the reproductive organs and heart.
A doctor may request a biopsy if imaging scans show a potential tumor in the lungs or stomach. During the procedure, doctors will remove a small sample of the fluid or tumor for lab tests. The results will confirm a mesothelioma diagnosis, and provide the best treatment plan.
There are a variety of treatment for mesothelioma, including chemotherapy and surgery. The majority of doctors use a combination of these methods. Patients could also benefit from taking part in a clinical trial of new mesothelioma therapies. To learn more about the trials, patients should speak with a mesothelioma specialist who has expertise in treating the condition.
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